A Brief Introduction to Sickle Cell Anaemia

Sickle cell Anaemia is a rare, genetic illness. It is a form of anaemia in which the red blood cells are incapable of carrying an adequate amount of oxygen in the body. It is an extremely difficult illness that is quite challenging to live with. Only the best hospitals can provide medication and treatment for the same. Let’s understand the various aspects around Sickle Cell Anaemia.

Blood carries vital nutrients throughout the body and also facilitates the exchange of gases, namely the intake of oxygen and release of carbon dioxide. The usual shape of the blood cells is just like a donut without any cavity inside. The bi-concave surface facilitates easy transportation of oxygen molecules. In case of sickle cell anaemia, the red blood cells resemble that of a sickle or crescent moon, thereby justifying the name.

This gives rise to 2 problems, inadequate oxygen supply, and the irregular shape of the cell leads them to get stuck in thin blood vessels, causing inflammation. A patient with sickle cell anaemia is likely to suffer one or more of the following symptoms.

  1. Anaemia that keeps on recurring and is closely followed by fatigue, and drained out of energy.
  2. Painful swells on feet, knees, and hands or other areas where the blood vessels are extremely narrow.
  3. Delayed growth which involves both natural and reproductive growth.
  4. High chances of gallstones, which often required gallstone operation to resolve.
  5. Poor vision that is purely due to blocked blood vessels reaching eyes.
  6. Frequent infections as this illness damages spleen, the organ that fights infections.
  7. Episodes of pain, particularly in chest, abdomen, and joints that lasts anywhere between few hours to few weeks.

Sadly there is no cure for sickle cell anaemia but with proper medication, it can be managed effectively through proper timely measures. The normal RBC has a lifespan of about 120 days, but the same reduces to 15-20 days for a sickle RBC. Needless to say, some of these patients require undergoing a periodic blood transfusion. These efforts along with proper medication can help the patient to get ease from the painful symptoms and to prevent the complications associated with the same.

Sickle Cell Anaemia

On this 19th June, as we witness World Sickle Cell Day, we encourage people with this illness to stay strong and seek treatment from time to time. Also, we salute the never-ending support of their family, the doctors and most important the blood donors for their contribution.